The opening of the shrimping season equals hard work for Elizabeth Murray and her fiancee's family here on a boat known as the Blue Waters.
However, they say this season is being overshadowed by what is looming in the background, and Murray says she's afraid their hard work will not pay off.
"People don't come up here because they don't know where to go. You know, they pull into construction. They don't think much of anybody's back here," said Murray.
To help ease those kinds of concerns, city leaders installed five 15-minute parking spaces on the east side of the harbor.
But the heavy construction is keeping those shrimpers docked on the west side out of sight, and they say, out of mind.
Many of them are already having to sell to local factories.
"It's hard work you know, and you go out there and only get 95 cents, a dollar, you know. When you sell to individuals you get 2 dollars for the medium, you know 4 dollars for the jumbos, so it's worth it you know. But, you know, it's just a bad area right now," said Murray.
An area Biloxi's mayor says the city is trying to remedy as soon as possible.
"A project of that size, a 250-million dollar project, is gonna be a temporary inconvenience. It doesn't make any difference where it's located you know. We're doing everything we possibly can to minimize the impact on the fishermen. We have put five parking spaces there. You know when the bottom floor is completed on the parking garage, then the people may park underneath there and open back up that area around there a little bit," said Mayor Holloway.
Mayor Holloway says the garage will open soon, and hopefully everything will be back to business as usual.